ࡱ> 352 bjbj *"__ '11111EEE8}$Et((******$N1N11cR11((Yiј^jy0S|(SS1HNN(S : Curriculum Vitae Osamu Shimomura (Aug. 27, 1928 Oct. 19, 2018) Born: Fukuchiyama, Kyoto-Fu, Japan Graduated Nagasaki College of Pharmacy, 1951 Ph.D. in organic chemistry, Nagoya University, 1960 Professional Experience Laboratory Assistant, Dept. of Pharmacy, Nagasaki University, 1951-1960. Visiting Researcher, Professor Hirata's lab, Nagoya University, 1955-1958 Research Associate (Biology), Princeton University, 1960-1963 Associate Professor, Nagoya University (Earth Science), 1963-1965 Senior Biochemist, Princeton University, 1965-1982 Adjunct Professor, Boston University School of Medicine, 1981-2001 Senior Scientist, Marine Biological Laboratory, 1982-2001 Distinguished Scientist, Marine Biological Laboratory, 2008-2018 Honors Fulbright Fellow, 1960-1963 Pearse Prize, Royal Microscopical Society, 2004 Emile Chamot Award, State Microscopical Society of Illinois, 2005 Asahi Prize, Asahi-Shinbun Cultural Foundation, Japan, 2007 Nobel Prize in Chemistry, 2008 Order of Culture, Japan, 2008 Honorary Doctor of Pharmaceutical Science, Nagasaki University, 2009 Honorary Doctor of Science, Gakushuin University, 2010 Honorary Doctor of Science, Boston University, 2010 Golden Goose Award, American Association for the Advancement of Science, 2012 Honorary Doctor of Science, Siberian Federal University, 2013 Fellow of the American Academy of Cancer Reserach, 2013 National Academy of Sciences, foreign member, 2013 Major Scientific Accomplishments Crystallization and chemical study of Cypridina luciferin, 1956 Discovery of aequorin and Aequorea green fluorescent protein (GFP), 1961 Structure determination of Cypridina luciferin, 1966. Isolation of Chaetopterus photoprotein, 1966 New term "photoprotein" proposed, 1966 Crystallization of Chaetopterus photoprotein, 1968. Structure determination of Latia luciferin, 1968 Structure determination of the aequorin luminophore, 1972-1974 Discovey of coelenterazine, 1975 Regeneration of aequorin, 1975 Confirmation of the dioxetane mechanism in the firefly bioluminescence, 1977 Structure of the chromophore of GFP, 1979 Semi-synthetic aequorins with various different Ca-sensitivities, 1987-1989 Structure determination of krill luciferin and dinoflagellate luciferin, 1988-1989 Superoxide-triggered luminescence of luminous fungi, 1992 Crystal structure of aequorin, 2000. Books Published Shimomura, O. (2006; 2012). "Bioluminescence: Chemical Principles and Methods," World Scientific Publishing, Hackensack, N. J., 500 pages. Shimomura, O., Shimomura, S., and Brinegar, J.H. (2017). Luminous Pursuit: Jellyfish, GFP, and the Unforeseen Path to the Nobel Prize. 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